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Chicago, Illinois · 2026

Physician Assistants Salary in Chicago, IL (2026)

Based on BLS data · Cost of living adjusted · Updated 2026 · 3 min read

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Average Salary

$147,213

per year

Cost of Living Adjusted

$137,582

effective purchasing power

vs National Average

+4%

national avg: $141,280

Salary Range in Chicago

25th %ile

$125,738

Entry

Median

$141,586

Mid

75th %ile

$170,867

Senior

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Physician Assistants in Chicago earn an average of $135,480, which is slightly above the national average of $130,490. While the higher cost of living in Chicago (107 index) reduces purchasing power to $127,074, strategic career moves can help PAs reach the top 25% earning tier of $158,092 or more.

Complete Physician Assistants Salary Guide — Chicago

Based on BLS data · Updated 2026

Salary Overview for Physician Assistants in Chicago

Physician Assistants working in Chicago have a median salary of $135,480, with the average matching this figure exactly. This represents a solid position in the healthcare market. The salary range is substantial: the 25th percentile earns $112,640, while top earners in the 75th percentile command $158,092. This $45,452 spread between the 25th and 75th percentiles indicates significant earning potential based on experience, specialization, and employer type. The year-over-year growth rate of 2.9% suggests steady demand and modest salary increases in the Chicago market.

Understanding Cost of Living Impact

Chicago's cost of living index of 107 means expenses are 7% higher than the national average. While your nominal salary of $135,480 appears competitive, your effective purchasing power is $127,074—about $3,400 less than the national average salary suggests. This matters most for housing, which is significantly elevated in Chicago compared to many regions. However, this doesn't mean the salary is inadequate; rather, it requires thoughtful budgeting. PAs should account for higher rent or mortgage payments, property taxes, and general living expenses when evaluating job offers or planning finances.

Comparison to National Average

At $135,480, Chicago PAs earn $4,990 more than the national average of $130,490—approximately 3.8% higher. This premium reflects Chicago's status as a major metropolitan healthcare hub with multiple large hospital systems, academic medical centers, and specialized practices. The higher local salary helps offset the increased cost of living, though not entirely. This positions Chicago as a favorable market for PAs seeking above-average compensation, particularly compared to smaller cities or rural areas.

Factors Affecting PA Salaries in Chicago

Several factors influence compensation in this market. Employer type matters significantly: academic medical centers and large hospital systems typically pay more than smaller clinics. Specialty selection is crucial—emergency medicine, orthopedics, and surgery-based specialties generally pay 15-25% more than primary care. Experience level directly impacts earnings; PAs with 5+ years in their specialty earn substantially more than recent graduates. Board certification and additional credentials can justify higher compensation. Geographic location within the Chicago area also plays a role, with downtown and affluent suburbs offering higher salaries than outer areas.

Strategies to Reach the Top 25% ($158,092+)

To reach the 75th percentile, consider these approaches: develop expertise in high-demand specialties like emergency medicine, orthopedic surgery, or cardiology. Pursue additional certifications or training that differentiates you from peers. Negotiate aggressively during hiring—many employers have flexibility beyond posted ranges. Gain 5-7 years of experience in your specialty before seeking top-tier positions. Target larger healthcare systems and academic institutions that typically pay premium salaries. Consider leadership roles or administrative positions that command higher compensation. Build a strong professional network within Chicago's medical community to access better opportunities. Finally, regularly benchmark your salary against current market data to ensure you're being compensated competitively.

Salary Distribution — Physician Assistants in Chicago

25th percentile: $125,738, Median: $141,586, Average: $147,213, 75th percentile: $170,867, National average: $141,280

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