Nurse Anesthetists Salary in Winston-Salem, NC (2026)
Based on BLS data · Cost of living adjusted · Updated 2026 · 3 min read
Average Salary
$198,777
per year
Cost of Living Adjusted
$225,882
effective purchasing power
vs National Average
-7%
national avg: $214,200
Salary Range in Winston-Salem
25th %ile
$167,819
Entry
Median
$197,339
Mid
75th %ile
$242,508
Senior
Compare across cities
See how Nurse Anesthetists salaries stack up in different cities side by side.
Nurse Anesthetists in Winston-Salem earn an average of $198,777, which translates to stronger purchasing power than the national average due to the region's lower cost of living. This guide breaks down salary ranges, local factors affecting compensation, and strategies to reach top earner status.
Complete Nurse Anesthetists Salary Guide — Winston-Salem
Based on BLS data · Updated 2026
Salary Overview
Nurse Anesthetists in Winston-Salem, North Carolina command an average salary of $198,777, with a median of $197,339. This means half the professionals in this role earn above this figure and half earn below. The salary range is substantial: the 25th percentile earns $167,819, while top earners at the 75th percentile make $242,508. This $74,689 spread reflects significant variation based on experience, credentials, and employer type. The field is growing at 5.7% year-over-year, indicating strong job security and expanding opportunities in the Winston-Salem market.
Cost of Living Advantage
Winston-Salem's cost of living index of 88 (compared to the national average of 100) is a major advantage for Nurse Anesthetists. This 12% lower cost of living means your salary stretches further here than in most U.S. cities. Your effective purchasing power reaches $225,882—significantly higher than your nominal salary. This translates to lower housing costs, reduced transportation expenses, and generally affordable healthcare and utilities. For context, a $198,777 salary in a city with a 100 index would provide less buying power. In Winston-Salem, you're getting more value for your earnings, making it an attractive market for this profession.
National Comparison
The national average for Nurse Anesthetists is $214,200, which is $15,423 higher than Winston-Salem's average of $198,777. However, this comparison is misleading without considering cost of living. When adjusted for purchasing power, Winston-Salem salaries are actually competitive. Your $198,777 in Winston-Salem provides equivalent or better financial flexibility than earning $214,200 in a high-cost area like New York or California. This makes Winston-Salem an excellent choice for maximizing both earnings and quality of life.
Factors Affecting Pay in Winston-Salem
Several factors influence Nurse Anesthetist compensation locally. Healthcare facility type matters significantly—major medical centers and surgical hospitals typically pay more than smaller clinics. Your credentials beyond the basic CRNA certification, such as specialized certifications or advanced degrees, command premium pay. Experience is critical; newly certified CRNAs start near the 25th percentile, while veterans approach the 75th percentile. Geographic location within Winston-Salem also plays a role, with positions at major institutions like Wake Forest Baptist Medical Center generally offering higher compensation. Shift flexibility and willingness to work nights, weekends, or on-call hours can increase earnings substantially.
Reaching the Top 25%
To reach the 75th percentile ($242,508), focus on these strategies: pursue additional certifications in specialized anesthesia areas like cardiac or pediatric anesthesia. Seek positions at larger medical centers or surgical facilities that handle complex cases. Build experience—aim for at least 5-10 years in the field before expecting top-tier compensation. Develop strong relationships with surgeons and physicians, as reputation drives referrals and opportunities. Consider leadership roles such as supervising other anesthetists or participating in training programs. Stay current with continuing education and emerging techniques. Finally, negotiate aggressively during hiring; many employers have flexibility in their offers.
Salary Distribution — Nurse Anesthetists in Winston-Salem
25th percentile: $167,819, Median: $197,339, Average: $198,777, 75th percentile: $242,508, National average: $214,200
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